I Am From

I'm from â€Å"Let's eat! † and â€Å"Man I sure am stuffed† Cheesy chicken spaghetti and rich death by chocolate. Burned bacon and slimy squash given to the dog to avoid eating. I'm from pineapple cheese pizza with caramelized pineapples atop And creamy chicken Alfredo with delicious golden strands of pasta. I'm from nana's homemade brownies and double chocolate chip cookies Stirred slowly and mixed with a â€Å"secret† recipe and baked with ark chocolate shavings For special occasions such as 4th of July parties and birthdays.FAMILY/MUSIC I'm from a song shared with Shelby. Air Guitar is our main profession. Driving in circles with the windows down Just to find the perfect song to live to Until we were pulled over for screaming the lyrics to We Can't Stop. I'm from Mac Miller blaring through my headphones and car speakers. I'm from Linkin Park. The Lumineers A Day to Remember And always: Maroon 5. Until I grew older and closer to God, and discovered TobyMac.I'm from a brown playful puggle we named Slade; Being lazy and sleeping on any soft surface in 2003. I'm from Alice, the playful powerful puppy. And Daisy our loveable Boston terrier Who chewed up all my socks with her sharp puppy teeth. And unfortunately had to be put down when my step brother was born.I'm from drinking hazelnut coffee beside Shelby on my front porch. Or near the sounds of the waterfall from the creek behind her house. I'm from Heather Hannel in Columbus, Ohio where horses run wild.Silly laughs and precious secrets shared between us. Heathers kindness and guidance Help me through life. I'm trom dreaming And living And my red 2001 Chevy Cavalier. I'm from The Voice And the Carroll family. I'm from wishing and playing and working at ArbVs. Like making roast beef sandwiches. And working with my best friend, Shelby. I'm from stormy Forks, Washington Beautiful Paris, Extravagant England, Exhilarating Disney World. I'm from here. Now. Face-timing my friend and typing my poe m.

Advanced Practice Nurse and United Kingdom Essay

Introduction The roles of the APRN are continuously evolving. From the early 1960s to present day, advanced practice nurses continue to rise to meet the needs of our communities and abroad. As the number of nurse practitioner-advanced practice nurses (NP-APNs) on a steady incline, the various barriers in defining their roles in the US as well as internationally has limited their ability to function at their full potential. As discussed in An International Survey on Advanced Practice Nursing Education, Practice, and Regulation (Pulcini, Jelic, Gul & Loke, 2009), NP-APN nomenclature, scope of practice and education are factors in the development of the roles of APRNs internationally. NP-APN Nomenclature The United States and United Kingdom both utilize the title of nurse practitioner; however, other countries, such as South Korea, Singapore, and Switzerland continue to use the title advanced practice nurse (Pulcini, Jelic, Gul & Loke, 2009). This can lead to confusion on the part of the patient and family member who may not be familiar with the role of the advanced practice nurse in the clinical setting. Also, the authors’ state that the United Kingdom uses the terms specialist and NP interchangeably. According to Pulcini et al (2009), â€Å"This interchange of terms most often occurs when the nurse who has specialized knowledge in a certain area has a advanced practice title (p. 32).† Scope of Practice As mentioned by Joel (2009), â€Å"The degree of autonomy afforded to APNs varies from country to country, and even within the country (p.76)†. The NP-APN scope of practice includes advanced health assessment, diagnosis, disease management, health education and promotion, referral ability, prescribing diagnostic procedures, medications and treatment plans, admitting and discharging privileges, patient caseload management, collaborative practice, evaluation of healthcare services, and research (Pulcini, Jelic, Gul & Loke, 2009). The United Kingdom and United States have similarities in their origins. Both were established to help meet the needs of the rural and underserved areas as well as the overall population. In the United Kingdom, NPs were utilized as the first level of care for patient triage and in primary care (Pulcini, Jelic, Gul & Loke, 2009). Another similarity is their prescriptive rights in both the US and the UK. According to Joel, â€Å"The move, originating in England, to enable nurses to undergo a specified nonmedical prescribing program has resulted in over 10,000 nurses who are now classed as independent prescribers, and as a consequence, can prescribe almost everything from the British National Formulary (p.90)†. Educational Requirements As in many professions, education is the key element to being successful and productive. The standard educational requirement for NPs in the United States in a master’s level degree; however in the United Kingdom is still trying to adopt a master’s level program. According to Pulcini et al (2009), â€Å"While the Royal College of nursing in the United Kingdom has developed a master’s curriculum for NP education, universities are not obliged to adopt it (p.33).† Furthermore, NP courses are both offered at the baccalaureate and master’s level in the UK. Conclusion The United States and United Kingdom have numerous similarities and differences in the roles of the APRNs. In the future, these roles will continue to evolve to meet the needs of the community.

The Hurt Locker

â€Å"The Hurt Locker† , written by Mark Boal and directed by Kathryn Bigelow. Nominated and won for Best Picture, this award winning movie captured the attending of many film makers and audiences for boldly demoing the rough world of war and how a soldier trades with the horrors of war. â€Å"War is a drug† , a quotation mark that this film successfully reflects in its narrative and subject. The soldier associates war as some sort of drug that one must take to for maintain traveling in life. This movie emphasizes this through James, chief supporter of the narrative, who is a changeless danger to himself and to others around him. The movie is about an American ground forces bomb disposal unit in wartime Iraq tasked with determination and demilitarizing bombs in order to protect the local public. The Hurt Locker besides focuses on their battles and triumphs in Iraq and portrays the life of the armed forces. Not merely does the Hurt Locker have a good narrative, but this movie besides implements many movie techniques such as elements of mise en scene, superb filming, and redacting. I will speak about how â€Å"The Hurt Locker† deserves to be an Academy Award victor citing these elements of movie. The ground why this movie is considered to be a great movie is because of its accent on movie technique. One of the elements portrayed in this movie would be the incorporation of Mise en Scene. There are many illustrations of Mise- En -Scene used to make a sense of pragmatism in the movie. One I would depict the ocular manner would be farinaceous. Everything from the scene to the costumes were reliable plenty that it added to the pragmatism of movie. In the beginning of the movie, I would depict the histrions as your typical jarhead in war movies. As the movie progressed nevertheless, they became instead complex. Each character has their ain sense of values, some want to remain in Iraq and battle because they believe it ‘s the right thing to make while others, like James, the chief supporter, loves being a soldier and wants to remain in the pandemonium everlastingly. The location of the filmed in Jordan, which is located a few chinks off from the Iraqi boundary line. This helpe d created the pragmatism and atmosphere it needed for movie to be reliable as possible, which audiences love in war movies. The scene that implements elements of Mise-en-scene would be the opening sequence of the movie. The movie opens with the citation â€Å"The haste of conflict is a potent and deadly dependence, for war is a drug† . The sequence is portrayed as a docudrama movie, holding the camera act as if it were describing a narrative on the soldiers instead than traditionally movie a scene. The camera motions were unsmooth and visuals were farinaceous. The lighting in this sequence was realistic, utilizing frontal lighting to an country to make a natural environment and the colour of the scene was impersonal, which gave the feeling that they were shooting in a existent state of affairs. Bing able to utilize mise en scene to convey a film’s message, subject, and symbols is such an enchanting experience, particularly with the Hurt Locker. Achieving pragmatism, yo u are able to steer an audience towards cardinal narrative elements, and therefore holding a viewer’s such as me to the full engaged. We want to cognize what it will be like to be a soldier like James and this movie was able to take us into the action. This movie was able to make the feeling of wonder and suspense which adds to the many grounds why this movie is great. Filming are one of the many movie elements that contribute to this film’s success. To hold a scene to be more cliff-hanging, the manager incorporated different types of camera angles. The scenes that focuses a character on a personal degree, the framing would be tight and concise. The most occurring thing in the movie are bombs, this represents how the bad the universe is. The soldiers themselves can be described as the 1s who are morally good and are praised for it because they are considered the chief focal point of the movie. I noticed that green and orange was the reoccurring colour subject of the full movie. These colourss represents the correlativity between peace and pandemonium in the movie. Green represents the goodness that the soldiers are conveying into the war. Orange is suppose to stand for the pandemonium and force that war brings to an country. The camera was invariably near to the action, giving more suspense to it. The distance of the camera in the establishi ng shooting is a bit stray as it tries to demo every portion of a given location, which makes every scene dramatic and shoves off ocular beauty for harsh, honorable pragmatism. The movie was shot on-location, so existent sunshine and fluorescents were used as the film’s beginning of visible radiation. The best illustration of light contrast would be the scene where there was a monolithic detonation. The fire was able to supply the light beginning and it absolutely contrast with the pitch black dark. The supermarket scene would be the 1 that would be the most critical portion of full movie. This scene’s filming was absolutely coordinated to convey the hollowness of the James as a individual. It portrayed the contrast of the movie by demoing James ‘s interior struggle between his civilian life and his life in the military. James has become person who instead put on the line his life in the battleground than populating a normal life. The scene would be the focal point of contrast between the two universes. In Iraq, danger is everyplace, poorness is prevailing, every measure you take could be your last. Then the scene’s scene alterations and see James walking around a supermarket. The topographic point is filled with nutrient and fundamentally the antonym of what it’s like in Iraq. This contrast portrays these universes as wholly different things. Another things to portray a contrast between the two universes would be the usage of colour. In the parts wher e it shows James in Iraq, the colour of sand is used to represents the grittiness of his life in the military. Everything from the edifices to the uniforms, they all portion the same colour. On the other manus, the supermarket’s usage of colourss is your typical colour strategy of an mean shop in America. The colour differentiation was done deliberately for to correlate the flaxen colour pallet of Iraq to dirtiness and the white colour strategy of the supermarket is associated with cleanliness. Cuting from Iraq to America emphasizes the nature seeking to get by with life with war and returning to civilian life. This was done on intent to hold the audience feel confused. One minute James is speaking about how he loves his occupation and another where James is back place, seeking brand assimilate back into the normal of a civilian. Overall, what James had to travel through in the supermarket scene can associate to many soldiers who have been consumed by the horrors of combat. To them, seeking to set to the normal life is merely excessively difficult for them. The supermarket scene describes that experiencing absolutely. The techniques implemented were able to acquire into the emotional province of a war torn soldier who’s urgently seeking to populate a normal life. The feeling of being changed after emotionally intense events and experiencing disoriented were drawn with elaborate preciseness. James may be a ticking clip bomb waiting to go on, but I think many soldiers can associate to what he’s been through. Editing can be a elusive, but powerful tool that enable film makers with a overplus of movie determinations. Surprisingly, â€Å"The Hurt Locker† had small redacting done on the movie, possibly that it wanted content, instead than organize. Alternatively of doing any â€Å"fancy† redaction to the movie, maintaining it to a minimum really preserves the pragmatism of its message. It takes advantage of some really simple techniques. In most movies, if non all of them, the length of the cuts depends on the state of affairs of the scene. The tempo of this movie was normally slow. Whenever something dramatic or emotional is go oning, the continuance of the shootings lengthen, to extended proportions. An illustration of this would be the conversation between Sanborn and James after the failed effort of demilitarizing the bomb from a suicide bomber. Sanborn snaps stating that he can no longer cover with the emphasis of being a soldier. This scene was the most critical in specif ying two different characters. Lengthening the shooting helped give a sense of pragmatism to the scene. During the action scenes nevertheless, the gait of the movie quickens and the length of the shootings shorten. This creates the haste needed to maintain the audience invested into the movie. ( CONCLUSION ) The Hurt Locker is a really powerful movie that deserves all the congratulations received of being an Academy Award Winner. The message that war can be used as a drug and soldiers themselves can be addicted to it has been prevailing throughout the movie. This dependence has soldiers such as James to value war over anything else, including household. Personally thought the film’s subject was interesting because it focused on that impact a batch of people. The movie has a good sense of projecting world of what it is. It’s non the typical film where it creates an semblance of phantasy where when the movie is over, the audience returns to world.

Montaigne's Apology for Raymond Sebond Essay Example | Topics and Well Written Essays - 1000 words

Montaigne's Apology for Raymond Sebond - Essay Example They are founded on ones capability to provide sufficient testimony to sustain such claims. He argues that anything can appear truthful or not depending on one’s interpretation and the amount of backing provided to support the claims. In Montaigne’s view, it is a person’s ability to provide irrefutable evidence, which determines if he or she appears stupid or clever, obscure or inconsistent. However, there is always the likelihood that someone else will dispute any idea, agree with it, or be at a tangent to it. In his opinion, Montagne argues that the different perceptions or considerations are what have given value to many things worth nothing. In this essay, the problematic issue is on the question of whether honey is sweet, or bitter. The discussion revolves around Heraclitus, Protagoras, and Democritus and Pyrrhonists opinions regarding the taste of honey. According to Heraclitus and Protagoras, honey has both qualities of being sweet and bitter. On the other hand, Democritus argues that honey is neither sweet nor bitter while Pyrrhonists claims not to know whether honey is sweet or bitter. This is an analysis of the different views regarding the reliability of senses as trackers of truth. Each of the four philosophers tries to support their own opinion. From the fact that honey was sweet to one and bitter to another Democritus and Protagoras drew their conclusion that it is neither sweet not bitter. In their opinion, sweetness or bitterness exists by convention. Sweetness or bitterness is thus not a quality of honey. Additionally they felt that attribution of traits or qualities are subjective affection that depicts our own perceptions regarding different things. In their view, honey is neither sweet nor bitter, the sweetness and the bitterness is an idea belonging to mind of the person tasting it. Bitterness and sweetness are two different things and thus it is not possible for something to have both qualities. Consequently, it is not possible for two conflicting opinions to be correct. The perception that something can be both sweet and bitter demonstrates that the language we use to describe things does not relate to anything in actuality. Qualities associated with different things are thus a mere depiction of our discernments and not the truth. Democritus and Protagoras opinion was different from that of Heraclitus who concluded that honey is both sweet and bitter. Heraclitus proposition was that â€Å"all things have in them features we discern† (Montaigne 147). By this, he meant that the attributes or traits associated with anything could vary depending on the person viewing it. Therefore, the qualities of bitterness and sweetness are in the honey but different people will perceive and describe them differently. For that reason, the opinions regarding anything depend on what the person wants to propose. There is thus no specific or constant outlook into anything. Heraclitus message was that our perce ption tends to be partial and thus the conclusion depends on one’s discernment but does not necessary mean it is the truth of the matter. Our senses are thus inadequate since they perceive whatever we want them to or want we want to advocate but not the reality. Pyrrhonian claimed not to know if honey is sweet, bitter, neither, or both. This opinion demonstrates doubts on whether any of the above quality exists or not. The

Use of digital technology Essay Example | Topics and Well Written Essays - 1000 words

Use of digital technology - Essay Example Rushkoff’s Program takes an equation of balancing the effects of technology for humanity. The program examines why it is necessary to view both ends of either programming technology or the effects of the technology itself.Rushkoff maintains that despite the fact that a lot has been commented on the effects of internet, whether bad or good, the society already has the internet to deal with its effects. Notably, the effects of technology can be either positive or negative depending on the application under consideration. Additionally, Rushkoff poses two critical concerns that are focused on whether to direct the technology or live under the direction of the technology (Engdahl 110). Shteyngart in his dystopia replicates the concerns evinced in the Rushkoff’s Program. The extremely sad true love story is a complete dystopia that recognizes the existence of digital technology. Therefore, this essay tends to analyze the effects of the internet or digital technology on social life in relation to this love story. Just like in the Rushkoff’s contributions, there are correlative results on any option one chooses in dealing with the rising of the digital technology. Internet is just as essential as the effects it may have on its users (Fraser and Soumitra 57). A complete control of how it is digested in its consumptions is a point of concern since the implications targeted may turn out to have propagated more harm than salubrious. It may involve the development of a system that both literary works espouse. The development of a system entails a number of processes... It also entails the modification, in which an existing system is improved in terms of its inputs and the interfaces (Fraser and Soumitra 89). Its software, hardware, procedure components, databases, telecommunications, and personnel are in the system design. The design also helps to understand the relationship that exists among these components. The next stage in the cycle is the implementation of the system. This is the most crucial stage in the system development cycle since it is here that the system plan is accomplished. All the preceding processes are meant to ensure that the implementation is effective. The components of the system are created in this stage in accordance to the design developed prior to this stage and put into operation where users undergo training on how to use the system (Engdahl 71). The result is a functional system that efficiently accomplishes the main roles that were intended. Program or system Maintenance is a regular process that aims at keeping the sy stem at par with its roles. Both the hard ware and software are maintained to keep their efficiency. Out of the mainstream, either Rushkoff or Sheytngart’s contribution to the understating the effects can help a lot in the social networking since a part of the concerns dealt through the net. The dynamism of online social networking can be considered as part of a human’s life. First, one gets to familiarize to the social networking issues. This ideal brings individuals together in groups with distinct or specific purpose in the community, and this contributes to what may be termed as social networking (Engdahl 126). They may include people of different diversities who share a common interest that they would love to espouse in their

Fashion Designer Parts 3 and 4 Essay Example | Topics and Well Written Essays - 1250 words

Fashion Designer Parts 3 and 4 - Essay Example The essay "Fashion Designer Parts 3 and 4" examines the role of fashion designer. Performance appraisals are not a kind of lecture that the supervisor gives to the workers. This kind of a meeting comprises of two-way communication, where the supervisors can enhance the efficiency of the workers not only by giving them feedback of their performance, but can also make the employees understand in which fields they can improve and how. Here the worker’s listening abilities are tested and it also provides the employees with an opportunity to seek any clarification they have regarding work. There are two methods to evaluate job performance of fashion designers, which can be measured using Barscale. Always ensure the availability of fabrics and apparels to facilitate the outline drawn previous to the commencement of the design production. They direct and coordinate the activities of personnel in â€Å"drawing, pattern making and sewing divisions† (Fashion Designer, n.d, par.8) to ensure the reflection of actual thought process of the designs created. Keep a keen eye on the changing global fashion trends and always remain updated with the latest trends. Usually draw inspiration and generate conceptual designs to propose extremely unique products. Occasionally provide direction and coordinate activities of personnel to produce original designs. Usually is aware of the changing fashion trend, but fails to be in synchronization with global design trends, pricing and preferences. Sometimes offers absolutely unique products.... Usually is aware of the changing fashion trend, but fails to be in synchronization with global design trends, pricing and preferences. Satisfactory: Sometimes offers absolutely unique products to the market by creating new designs, but often fails to keep abreast of consumer preferences. Outlines the designs to be created but does not ensure the availability of fabrics and apparels required for the production. Poor: Poor direction and coordination of activities of personnel. Fails to develop marketing strategies required to penetrate into new markets as well as lacks creativity and innovation in designs? 2. Behavior: Proper Communication with Supervisors, Peers and Customers Regarding Design Ideas, Establish and Maintain Customer Relationship Excellent: Always communicates with supervisors, subordinates and also with the clients of the organization. Designers often take advantage of the information gained from the discussions and knowledge regarding fashion to produce unique designs. Frequently coordinates with clients to get an insight into their tastes and preferences as well as get an idea about their outlook on the designs and make any alterations required as per their demand and also maintains excellent relationship. Better: Usually provides sample garments to display at fashion shows, but little communication with the supervisors, subordinates and clients. Better utilization of the information attained from the discussion with various groups, however a less preferences is given for the customer’s tastes and choices. Good: Sometimes there is communication with the supervisors, subordinates and clients, but mostly failure to make use of the information obtained from discussion. Provides sample garments for exhibition at fashion shows, often fails to

Ethics and the college Student Essay Example | Topics and Well Written Essays - 750 words

Ethics and the college Student - Essay Example These resources are used to enhance and promote conversations and curricula on issues relating to ethics designed for college students, staff, and even the administration. Among the code of ethics include integrity which is to be present in any manner of relationship. Moreover, must treat others in respect, fairness and honesty. Competence is paramount any college for it to realize its educational objectives. Students in any college are to ensure equality and acceptance so as to prevent harassment, discrimination, and intimidation. Finally, it is honor and trust in all academic assignments thus avoiding plagiarism in any given assignment. Discussion A code of ethics must be there in colleges so as to curb cheating and related vices. Cheating is an epidemic in most of the colleges as it affects almost fifty percent of the total student population. The code of ethics is affected by the social characteristics and demographics of students like sex, age, levels of test anxiety, academic s tanding, and internal social control. Thee factors have been found to contribute to cheating in colleges which is unethical (Loveland & Rayna, 2000). This is because many students have rationalized their behavior in cheating and they do so without having to challenge the norm of honesty that is required. Most of the commonly cited technique they use is the denial of responsibility. In addition they use the neutralization technique of appealing to the higher loyalties. Here, they have been arguing that it is more vital to aide a friend than to avoid cheating which quite unethical. By the students recognizing and accepting cheating as a very undesirable behavior but nonetheless they see it as an excuse under certain circumstances thus the presence of situational ethics. To some students cheating is planned, expected and their opinion it is rewarded by good grades. This leaves the ethics and internalized control of the student as a barrier to cheating (Corll, 2007). However, the neutra lizing attitude gives the students the green light to side step issues of guilt and ethics and going ahead to place the blame for their behavior on another front. This concept of neutralization in relation to the ethics of college students permits them to state that cheating is wrong but to some extent in special circumstances it is acceptable, and even necessary. David Matza and Gresham Sykes (1957) are the first who developed the concept of neutralization so as to explain the concept of delinquent behavior. They explained the expression of delinquent behavior through the process of situationally defining deviant behavior in this case the college students through naturalization justify the violation of accepted behavior (Labeff et al, 2010). Plagiarism is considered as an act of dishonesty in academic spheres whereby a person takes the work of others and presents them as his or her own without proper attribution. Plagiarism can have numerous effects on both the student and the educ ational sector as a whole. Plagiarism leads to the student failing to develop sharp critical thinking skills which are paramount in any learning process. Also, it damages the relationship between the students and teachers by eroding their mutual trust and the students who legitimately earn their grades. Plagiarism can lead to loss of a degree or a job. This includes the college students, the college faculty members who may plagiarize the work of other scholars, and finally professors who face

THE INFLUENCE OF SOCIAL NETWORKING SITES (SMS) ON THE INTERPERSONAL Research Proposal

THE INFLUENCE OF SOCIAL NETWORKING SITES (SMS) ON THE INTERPERSONAL RELATIONSHIPS OF STUDENTS - Research Proposal Example He attributes this phenomenon to the ability to communicate with people having a set of common interests using SNS technology. For instance, SNS allow users to form groups based on a specific subject, allow private communication among select people and provide features to show or hide specific user information and messages based on a set of predefined rules. Such components allow users to establish and nurture virtual relationships regardless of geographical location. This virtual relationship among two or more individuals can be based on various factors including past associative history (classmates, neighbours etc.), love, business or any other form of social interaction. Traditionally, interpersonal relationships were limited to physical interaction through scenarios such as family, marriage, employment, social clubs etc., most of which come under the purview of legal frameworks, constraints and scrutiny. Social networking however is not restricted entirely within any of these boundaries and even facilitates the establishment of relationships among individuals who may have never met or seen before physically. Ozok (2009) stresses that this excitement behind the possibility to meet new people, particularly of the opposite sex, that encourages students using socials networking. He further adds that virtual interactions through SNS are also capable of influencing the relationships of users with people close to them and can be either good or bad i n the nature. The paper is a research proposal for studying the use of social networking among students in the age groups of 13-17 years. The proposed research topic was selected as it is evident that social networking is extremely popular among students and develops a major proportion of their activities performed through the Internet. Chatting with friends, posting messages or sharing photographs are some of the tasks that

Investigate the ways in which the film Inception both uses and Essay

Investigate the ways in which the film Inception both uses and subverts the genre conventions - Essay Example Origin is in view of the essential motivation that a solitary thought in a singulars psyche can be either the most significant resource or the most perilous weapon (McConachie, 2008). The film stars Leonardo DiCaprio as Dom Cobb, who in the motion picture takes data from the psyches of his victimized people amid dreams. The last employment which Cobs is given, and which is the inside of the motion picture includes execution of an initiation so that Cobbs could recover his past life and have the capacity to visit his youngsters. The film largely got exceptional acclaim as an imaginative shrewd story and numerous commentators issued its positive surveys. Spoiled tomatoes for the case gave this film a normal score of 8/10 in view of more than two hundred and fifty surveys and reported that up to 86% of pundits gave this motion picture a positive review (Rottentomatoes.com, 2015). Particularly applauded in this film is the maker, executive or author, Mr. Nolan, who got numerous positive notification and compliments even from the best commentators. Case in point, a remarkable pundit, Peter Travers from the Rolling Stone magazine complimented this motion picture and Mr. Nolan expressing that it was similar to a keen chess amusement. Justing Chang who said that the essayist connected the best ability to distinctively portray the procedural point of interest of sub-awareness, very much a surrealists thriller which gave all the viewers a major test to investigate the unpredictable and profound working of the psyche , has commended the authors aptitude (Carson, 2008). The class of this motion picture is broadly translated. Some perspective it as riddle and anticipation, while different people classify it as Drama, activity, or experience (Carson, 2008). Much the same as whatever other motion picture, the issue of such a kind has been liable to the different

Mexico Case Study Example | Topics and Well Written Essays - 1750 words

Mexico - Case Study Example Large numbers of multinational automobile manufacturers are either shifting their base from Canada to Mexico or are limiting their operations in Canada and expanding the same in Mexico (Althaus â€Å"Mexico Sets Auto Production Record, Aims for More†). Mexico has gained significant attention of automotive producers, as a result of several factors that deliver geographical and other competitive advantages to manufacturers. These advantages include extremely low wage rate, free trade agreements with approximately 45 countries across the globe, well-developed transport system with year-round ice free coastal ports and high level of financial incentives from Mexican government. Owing to these features, global automakers announced investment of $7 billion in Mexico as opposed to $750 million in Canada. Mexico’s stable and lucrative business environment has caused most automakers to adopt global strategy for business expansion (Keenan â€Å"Mexico races ahead in auto industry as Canada stalls†). Contextually, it is imperative to comprehend the distinction between international and global strategies even though they are frequently used interchangeably. These differentiating factors are degree of central involvement and coordination in strategic activities, degree of standardization in products and responsiveness towards local business environment and strategic integration and competitive steps. Since internationalization in Mexico is mainly about achieving competitiveness in production and operations, almost all companies adopt global strategy (Twarowska and Kakol 1005-1011). Under the purview of global strategy, most automakers ensure and exercise central control over production in Mexico and as automotive industry is about ensuring standardization in products, global strategy is most effective herein. Unlike international

The Paralegal Profession Essay Example | Topics and Well Written Essays - 1000 words

The Paralegal Profession - Essay Example Lawyers who handle high profile, media-friendly cases gain the distinct advantage of demanding higher pay and accolades, particularly those who win more cases than their peers. Becoming a lawyer involves a lot of hard work and preparation for students who wish to pursue this career. To begin with, prospective law students must take up a pre-law course, majoring in any field of their choice, before they can proceed to their law degree. Law schools do not require any prerequisite courses for admission. However, most students choose among accounting, economics, philosophy, history, composition and literature, psychology, sociology, political science, religion and logic as their pre-law courses (Abernethy. 1996). Potential law students have many options at their disposal that will enable them to make an informed decision on whether or not to proceed with their desire to pursue a law degree or not. For example, they can sit in on a class or two to get a feel for what is expected from students in a typical law class. They may also join a tour of any law school of their choice or meet with current law students, if they are interested. Abernethy, A. J.D. Ph.D. mentions another option, which is, to â€Å"shadow† a lawyer, following him around for a day or two, just to have an idea of what a typical day for a legal professional is like. It is vital to remember that a lawyer’s daily schedule differs from one day to the next, ranging from a day in court to a long day at the library researching for a case. It is also important to note that the legal profession offers a wide range of fields—from commercial law to tax law to human rights law—so it would help the student considerably if he or she can shadow more than one lawyer (1996). Some students also get the chance to work as â€Å"runners† in a law office before they begin law school. â€Å"Runners offer general clerical assistance but their function usually entails filing papers at the

The Love Song of J. Alfred Prufrock by T. S. Eliot Essay Example for Free

The Love Song of J. Alfred Prufrock by T. S. Eliot Essay The Love Song of J. Alfred Prufrock (or simply Prufrock) is T. S. Eliot’s most popular poem and it is the one responsible for the launch of his career as one of the 20th century’ leading and influential poet. The poem takes the form of a dramatic monologue and it is considered as one of the most anthologized poem in the 20th century.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Prufrock is a poem which made use of lots of literary devices such as similes, personifications, repetitions, allusions, imageries and the like, all of which contributed a great deal to the tone of the poem which is miserable and unhappy, it also helped contribute to the theme of indecision (which led to lots of missed opportunities), sexuality, and paralysis. For one the use of simile is clear in the following line, â€Å"when the evening is spread out against the sky like a patient etherized upon a table† (Eliot, 1917) and it skillfully illustrates the solemn outdoor setting in contrast to the party setting which would later on take place in the poem.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Repetition is one of the most essential tools used by Eliot in the poem. For one, in the following stanza â€Å"In the room women come and go talking of Michaelangelo† (Eliot, 1917), Eliot brings the audience to the place Prufrock himself finds himself tied into, and this particular repetition contributed a lot in setting the tone of the poem as it shows the readers how Prufrock muses on how he wants to tell a woman how he truly feels and yet for some melancholic reason, he cannot.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Upon reading the poem one could envision that Prufrock is not really that old, he is probably a middle-aged man who is trying to examine what went wrong with his life, or trying to look back to the choices he made at the course of his life. Among the things he constantly look upon is the things he did not do, his regrets for acting the way he did, for his indecisions, and most of all he is looking back on his failure with regards to women thus one could then on say that one of the primary tones of the poem is that of a tired, ironic self-criticism. The character of Prufrock made many references on his going bald, most notably was a scene with a reaper who is holding his coat for him so that he could then on leave this material world. Prufrock tried to make himself feel what it is like to be young again one notable example was when he tried to dress and fashion his hair the way young men does. However, in spite of this particular endeavor he knows deep inside that it is no use since he would no longer be young again and this particular fear of approaching old age contributed a great deal to his paralysis which is the primary theme of this poem.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   From the title of the poem alone one could have an idea that Prufrock is no ordinary or traditional love poem. Prufrock then is a ludicrous name and the author wants the subconscious implication of a prude in a frock. The original title of the poem is actually Prufrock Among Women and this particular emasculation added a certain depth to the themes the author would delve into which rotates around the notion of paralysis and heroism. As was mentioned earlier this poem takes the form of a dramatic monologue in which the speaker unconsciously reveals a part of himself to the silent readers. The poem shows a great deal of Prufrock’s inability to commit and express himself to women or to love, or to other individuals for that matter.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The 2st stanza of the poem hints that Profruck and a companion are out for an evening walk. Most of the themes and tone of Profruck illustrates profound melancholy and lack of communication or inability to express himself. The city discussed in the poem appears gloomy, it seems to portray the city in a half dead, desolate, and lonely feel. The streets seems to curve to a particular conclusion or question and it seems to ask if the protagonist should dare to assert himself or to reach out and try to communicate with other people.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The fourth stanza of the poem implies to life’s triviality as could be seen on the following line â€Å"hundred indecisions†¦before the taking of toast and tea†. The readers could then envision Prufrock worrying himself over life’s trivialities such as what tie to wear at the party and what words he should use to strike up a conversation (presumably with a woman) at the party. The women the protagonist is about to meet at the party are belittled in that their primary use is to serve as some kind of a decoration and keep shallow conversation going all throughout the party as could be seen on the following line â€Å"that lift and drop a question on your plate† (Eliot, 1917).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   In the sixth stanza of the poem one could envision the protagonist hesitating on whether he should continue to climb the stairs which would take him to the place where the party is being held, he keep on worrying on whether he should â€Å"dare† communicate or try to reach out to these people. In the seventh stanza the protagonist was pondering about the things he did or the trivialities he did in his life and it also shows that he knows what kinds of people would be present at the party. He knows that those people are full of life’s superficiality. These particular people were further singled out in the 9th stanza as women of women on which the protagonist seems to posit an attitude synonymous to sour-graping.   Upon close observation the readers would then on see that these elegant women have hairy arms, however, in spite of that these women still have some kind of an effect to the protagonist of the poem as could be seen when he was not able to organize his thoughts which is being diverted by the smell of the perfume of these women. It is important in this line to notice that Prufrock does not treat these women as a whole people but rather merely as part of their physicalities which attracts and mislead other people as could be seen on the following lines, â€Å"eyes that fix you in a formulated phrase†, â€Å"faces that you meet†, voices dying with a dying fall† (Eliot, 1917) and the like.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   On stanzas 79-80 the protagonist was once again pondering on whether given lots of empty times should he try to assert his personality and try to reach out to other individuals. Mainly because the protagonist talked a great deal about women on his earlier stanzas one could then assume that the line â€Å"force the moment to its crisis† (Eliot, 1917) have an innuendo of sexuality because whereas the inability to communicate himself appears to be the primary theme of the poem, the protagonist incapacity to have sexual relationship is taken care of in a more specific manner. If someone is incapable of having sexual relationship with another individual, he is cut off from the some things considered worth while in life and the protagonist is portrayed as someone who is incapable of making a move on a woman (he could not even reach out to converse to any people, much less a woman) because of his fear to look ludicrous in front of them.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The protagonist inability to make use of the time or opportunities given him is signified by the past tense found in the twelfth stanza. In this stanza the readers would be able to see that if the protagonist indeed tries to reach out to people particularly to the woman he likes he would only appear preposterous and these people would not even be able to understand him. In stanzas 95-97 the protagonist made an implication that he ever approach or make any kind of insinuation to a woman â€Å"roll†¦strength and all..sweetness up into one ball, and tearing†¦pleasures with rough strife † (Eliot, 1917) there is a huge chance that he would be misunderstood and worst they would be disgusted with him and put him off. All of these reasons among many others seem to answer the earlier question on whether he should dare to assert himself. The protagonist states â€Å"No!† because he sees himself as insignificant, he is so full of self-consciousness and because of that he is unworthy of â€Å"disturb(ing) the universe† (Eliot, 1917).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Now that the fundamental question of him asserting himself has finally been answered the protagonist is once again seen to be looking at what his life would be like (he would grow old and bald) and he would also wonder if he has the guts to eat a peach â€Å"do I dare to eat a peach† (Eliot, 1917). This particular line could be viewed in different manners one of which is that fresh fruit because of digestive problems however, the peach could also be seen to have an underlying sexual connotation. Fruits in general have a sexual connotation as the ripened ovary of a plant and peach in particular holds more sexual connotation because of its flesh like color, its soft texture and its downiness. The peach’s shape and texture symbolizes the female genitalia thus one could see in the line mentioned above that the protagonist is wondering that if he is unable to sexually assert himself to a woman while he was still in the prime of his life, how else would he be able to sexually assert himself when he becomes an old man. Peach also have other meanings. Peach is the Chinese symbol for marriage and immortality, both of which the protagonist so want to have in his life. As could be seen then, the protagonist pondering on whether he would dare eat a peach has got something to do with his sexual ineptness. As the poem ends, the protagonist was imagining mermaids, oe men’s ideal dream of women sitting on the beach, however, in spite of the fact that it only happened on his imagination, the mermaids still did not sing for him. When the protagonist was awakened from his dream by a human voice one could then conclude that even in dreams, the protagonist is still paralyzed and non-active. This particular paralysis, the protagonist’s inability to act and to grab at the opportunities given to him by life is the primary theme ever present in The Love Song of J. Alfred Prufrock. Works Cited Dempsey, Jough. â€Å"The Love Song of J. Alfred Prufrock by T. S. Eliot.† (1997).   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   February 28, 2008 http://articles.poetryx.com/7/. Eliot, T. S. â€Å"The Love Song of J. Alfred Prufrock† (1917). February 27, 2008   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   http://www.bartleby.com/198/1.html. Moody, David. The Cambridge Companion to T. S. Eliot. Cambridge UP, 1994. Scofield, Martin. T. S. Eliot: The Poems. Cambridge UP, 1988. Uncgrad. â€Å"The Love Song of J. Alfred Prufrock.† (2007). February 28, 2008   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   http://www.associatedcontent.com/article/113548/the_love_song_of_j_alfred_ prufrock.html.

Kappa Agonists in Management of Pain and Opioid Addiction

Kappa Agonists in Management of Pain and Opioid Addiction Joseph Nguyen Abstract Hypothesis: Opiates mediate pain via opioid receptors, which consist of several subtypes. One subtype, the kappa opioid receptors (KOR), has also been shown to prevent addictive behaviour. Potential novel therapeutic compounds acting on KOR include U50488, CR665, and CR845. It is hypothesized that selective kappa opioid receptor agonists are effective at controlling pain while managing opioid addiction. Methods: Studies for this review were obtained through the PubMed database using a keyword search strategy. Only articles in English published from December 2006 until December 2016 were considered. Results: Kappa agonists are able to decrease inflammatory, visceral, and surgical pain, but are unable to inhibit behaviour-depressing aspects of pain. Kappa agonists also decrease field potential and long-term potentiation in the basolateral amygdala. Additive anti-nociception with mu opioids has been observed as well as decreased fentanyl use, morphine tolerance development, and morphine withdrawal symptoms. Conclusions: Kappa agonists can be effective analgesics while also preventing abuse and addiction to mu opioids. Some evidence also suggests kappa agonist activity in the basolateral amygdala can inhibit affective components of pain. Abstract Word Count: 175 Keywords: kappa agonist, pain, analgesia, anti-nociception, tolerance, dependence, withdrawal, addiction Ultramini Abstract: This study reviewed current research on the analgesic and anti-addictive properties of selective kappa agonists for their use in pain management while preventing addiction. Introduction Opioids are one of the most powerful analgesics available with an increasing trend of prescription in the United States. Prescriptions per capita increased 7.3% from 2007-2012 with 259 million prescriptions in 2012, enough for one bottle of opioids per adult (Dowell et al., 2016). On the other hand, use of opioids presents risks including dependence, abuse, addiction, and overdose which lead to negative health, social and economically impacts. From 1999 to 2014, over 165,000 people have died from opioid overdose and in 2013; an estimated 1.9 million people abused or were dependent on prescribed opioids (Dowell, Haegerich Chou, 2016). However, pain treatment should not be ignored as there are clinical, psychological, and social consequences associated with chronic pain including limitations in complex activities, lost work productivity, reduced quality of life, and stigma, emphasizing the importance of appropriate and compassionate patient care (Dowell et al., 2016). The CDC has recently released a guideline, aimed at primary care settings, suggesting prescriptive protocols as well as methods to evaluate risk of patient substance abuse and addiction. However, the majority of evidence reviewed by the guideline had significant limitations. Although the CDC guideline still has value in preventing exacerbation of pre-existing risk of abuse, results and implementation remain to be seen. Efforts have been made to deter abuse through novel drug formulations, barriers, and pharmacokinetics. Nevertheless, nothing can prevent an addicted person from taking multiple doses at once. This may be a result of the inherent nature of the drugs to activate reward pathways in the brain along with its analgesic effects though mu receptors. Another opioid receptor, kappa-opioid receptor (KOR), has been shown to limit motivational properties of drug abuse (Lalanne, Ayranci, Keiffer Lutz, 2014). This has sparked interest in development of kappa agonists as novel analgesics with low abuse potential. Examples of known selective kappa agonists include U50488, CR665, and CR845 among many others including those continuing to be developed. However, questions still remain about analgesic efficacy and complications for patients already addicted to mu opioids transitioning to kappa agonists. This literature review explores the anti-nociceptive efficacy of kappa agonists and their ability to m anage opioid addicted patients. Balancing adequate pain control with risk of future abuse has been a difficult endeavour for physicians as well as patients. This topic was chosen to investigate the possibility of a potent pain medication without addictive properties as an alternative to traditional mu opioids. Surely, this would be a major instrument in the treatment of chronic pain. This study will be done under the hypothesis that kappa agonists are effective in management of pain and opioid addiction. Methods A search was performed for published literature on PubMed. Search terms were selected to assess analgesic properties and anti-addiction properties of kappa agonists on opiate use (Table 1). The search terms used included: pain, chronic pain, kappa opioid, kappa agonist, pain control, anti-nociception, withdrawal, dependence, addiction, and tolerance. This study looked at articles in English published between December 2006 and December 2016. Articles of all levels of evidence were considered and included review, preclinical, and clinical data. The initial search produced 574 results. These resources were then screened with the following exclusion criteria: articles not involving kappa agonists/receptors, articles on opioids without kappa receptor selectivity, articles on opioids with dual agonist activity, articles on kappa agonist interaction with drugs that were not analgesics. Abstract reviews of the remaining articles were performed to select for articles on analgesic efficacy or anti-addictive properties of selective kappa agonists. The resulting collection of evidence was organized into an evidence table (Appendix). Table 1-Keyword Search Strategy Population Intervention Comparison Outcome Pain OR Chronic Pain Kappa opioid OR Kappa agonist Analgesia OR Analgesic OR Pain control OR Antinociception OR Anti-nociception OR Withdrawal OR Dependence OR Addiction OR Tolerance Results A final total of 11 articles were included in this study, the majority being animal studies on mice or rats. One study involved rhesus monkeys. There was one study that involved a human clinical trial. Also, there was one review using human clinical trials focused only on peripherally selective kappa agonists. Table 2-Summary of Study Designs Reviewed Study Design # of Studies Animal Models 9 Clinical Trials 1 Review 1 Analgesic Efficacy An animal study by Auh and Ro (2012) induced inflammation in rat hindpaws with injections of complete Freunds adjuvant. After 3 days, when mechanical hyperalgesia was well developed, local injections of kappa agonist U50488 were given at different doses and mechanical threshold for hindpaw withdraw response was measured. The results showed dose-dependent increase in mechanical threshold by local injections of U50488 (Auh Ro, 2012). A time effect was also observed where increasing doses of U50488 prolonged the anti-hyperalgesia effect. The role of kappa opioids in inflammatory pain was also studied by Moon et al. (2016) in a research on the effects of peripheral kappa opioid receptors and arthritic pain. Arthritis was induced in rats using 1% ÃŽÂ »-carrageenan injected into the knee. After nociceptive behaviour was maximally expressed (reduced weight-bearing in ipsilateral joint), U50488 was injected into affected joints. A two-way repeated-measure ANOVA showed significant recovery of reduced weight-bearing in the affected limb in comparison to saline. In addition to inhibited nociceptive behaviour, U50488 was also found to reduce mechanosensitive afferent nerve fibre activity in the carrageenan-induced inflamed knee using nerve recording techniques. Aside from inflammatory pain relief by U50488, the peripheral kappa opioid CR665 was found to significantly increase pain threshold to esophageal distension in a study by Arendt-Nielsen et al. (2009). This randomized, double blinded, controlled study compared the effects of CR665 against oxycodone on skin, muscle, and visceral pain stimulation in healthy males. Although CR665 increased pain threshold to esophageal distension, oxycodone had the same effect with addition to increased pain threshold to cutaneous pinch pain, cuff pressure pain, and thermal stimulation. A number of other clinical trials, on peripheral kappa agonist CR845, were reviewed by Albert-Vartanian et al. (2016). A randomized, double-blinded, placebo-controlled study was conducted on elective hysterectomy patients for analgesic efficacy before and after the procedure, using a 10 cm visual analog scale for measurement of pain intensity. If pain persisted after 24 hours, rescue medication (IV morphine) was given. Significant differences were observed in comparison to patients who only received placebo. Less use of rescue medication as well as a 2-fold decrease in pain intensity was found in patients that received CR845 before and after the surgery. Albert-Vartanian et al. (2016) also discussed a phase 2, randomized, double-blinded, placebo-controlled clinical trial in patients electing bunionectomy surgery with fentanyl as rescue medication. Over a 48 hour period, pain was measured regularly using a visual analog scale. The study used a sum of pain intensity difference from baseline levels over 24 hours (SPID ­0-24) as a measurement for efficacy along with SPID0-36 and SPID0-48. In patients who completed the study, there was a statistically significant reduction in SPID0-24 and SPID0-48 in those treated with CR845 compared to placebo. However, there was no significant difference in the modified intent-to-treat group. In another phase 2 trial, patients with moderate to severe osteoarthritis pain (>4 out of an 11 point scale) were given an oral form of CR845 with acetaminophen as a rescue drug over 2 weeks (Albert-Vartanian, 2016). A dose-dependent reduction in average pain score of 25-34% was observed. Among patients receiving the highest dose of CR845, 50% had a reduction of †°Ã‚ ¥30% in their reported pain score at the end of the 2 weeks with an 80% reduction in requirement for acetaminophen. Analgesic Efficacy with Other Measures of Pain Aside from sensory components of pain, there are affective and behavioural components of pain as well. An electrophysiological experiment conducted by Huge, Rammes, Beyer, Zieglgansberger, Azad (2009) looked at the effects of kappa opioid receptors activation on mice basolateral amygdala, an area of the brain that is involved in pain processing and pain memory formation. The field potential amplitudes were measured at baseline and under induced long-term potentiation using high frequency stimulation and the effects of kappa agonist U50488H were studied.   The experiment found that U50488H decreased baseline levels of field potential amplitude as seen in Figure 1, while these effects were inhibited by kappa receptor antagonist norbinaltorphimine (nor-BNI). Figure 1. Effects of Kappa Agonist and Antagonist on Field Potential Amplitude of Mice Amygdala. Baseline (BL): 100 ±0.5%; U50488H: 86.3 ±2.4%, nor-BNI: 100 ±4.2%. Data points show average field potential (FP)  ± Standard Error. Reproduced from Huge et al., 2009, p. 125. Prior application of U50488H before high frequency stimulation was also found to inhibit induction of long term potentiation (Figure 2) in comparison to long term potentiation induction with no drug (Figure 3). Figure 2. Effect of Kappa Agonist Pre-treatment on High Frequency Stimulated Long Term Potentiation of Mice Amygdala. U50488H: 100 ±4.1%; High Frequency Stimulation (HFS): 102.6 ±7%. Data points show average field potential (FP)  ± Standard Error. Reproduced from Huge et al., 2009, p. 126. Figure 3. Long Term Potentiation Produced by High Frequency Stimulation. Baseline (BL): 100 ±2%, High Frequency Stimulation (HFS): 119 ±4%. Data points show average field potential (FP)  ± Standard Error. Reproduced from Huge et al., 2009, p. 126. Although pain-stimulated behaviours are often used as a measure of pain, such as a withdrawal or writhing response, complementary measures are behaviours that diminish in the presence of pain stimuli (Negus, OConnell, Morrissey, Cheng Rice, 2011, p. 506-507). An experiment by Negus et al. (2011) studied the effects of peripheral and central kappa agonists compared to ketoprofen on rats trained to evoke intracranial self-stimulation using a lever, a behaviour that is depressed by pain. Intraperitoneal lactic acid injection acted as a pain-inducing stimulus, with a stretch response being a pain-stimulated behaviour to contrast with the pain-depressed behaviour of intracranial self-stimulation. It was found that the central kappa agonist (salvinorin A), peripheral kappa agonists (ffir and ICI204448), and ketoprofen all inhibited lactic acid induced stretching. However, only ketoprofen inhibited lactic acid induced depression of intracranial self-stimulation. Salvinorin A had actually i ncreased depression of intracranial self-stimulation while ffir and ICI204448 had no appreciable effect. Similar results were found when Negus et al. used depression of nesting in mice as a measure of pain (2015). Kappa agonist U69593 failed to both inhibit and reverse depression of nesting induced by intraperitoneal lactic acid and intraplantar complete Freunds adjuvant (Figure 4A 4B). However, 1-way ANOVA analysis (pFigure 4A 4B). U69593 was shown to actually depress nesting when administered independently (Figure 4C) and this effect was not able to be reversed by neither ketoprofen nor morphine (Figure 4D). Figure 4. Effects of Ketoprofen, Morphine, and U69593 on Nesting under Different Conditions. Panel A: Nesting depressed by intraperitoneal administration of 0.32% lactic acid. Panel B: Nesting depressed by intraplantar administration of complete Freunds adjuvant. Panel C: Nesting under no treatment. Panel D: Nesting depressed by U69593. Nesting represented as the number of zones cleared of nesting material. V represents drug vehicle only. Darkened points represent significant difference from drug vehicle under given condition. Reproduced from Negus et al., 2015, p. 18.       Interactions with Mu Opioids There is evidence suggesting kappa agonists have anti-addictive effects (Lalanne et al., 2014). However, it is important to evaluate the effects of kappa opioids in concurrent use with mu opioids. A study on interactions of fentanyl and U69593 in rhesus monkeys showed a decrease in the rate of drug self-administration when the kappa agonist was added to fentanyl compared to fentanyl alone (Negus, Schrode Stevenson, 2008). This effect increased with greater proportions of U69593 in the mixture (Figure 5). Using a conditioned response for food as a measurement for activity, both fentanyl and U69593 alone depressed the behaviour while mixtures showed a less than additive effect. Furthermore, at the lowest proportion tested (0.22:1 U69593/fentanyl), U69593 reduced the behaviour depressing effects of fentanyl. Figure 5. Rate of Self-Administration of Fentanyl vs. Dose of Fentanyl, U69593, or Mixture. Reproduced from Negus et al., 2008. Negus et al. also demonstrated additive thermal anti-nociception, using tail withdrawal threshold from heated water, with the fentanyl/U69593 mixtures at all proportions tested (2008). More evidence of additive effects of kappa and mu opioids was shown by Sakakihara, Imamachi, Saito using a similar method in mice (2016). Intrathecal injection of kappa agonist TRK-820 combined with morphine resulted in a stronger anti-nociceptive effect compared to morphine alone. Compared to morphine alone, kappa agonists also have benefits regarding the development of tolerance. It is well known that repeated use of mu opioids quickly develops tolerance. The addition of a kappa agonist has been shown to inhibit the development of tolerance to morphine (Hamabe, Yamane, Harada Tokuyama, 2008). Mice treated daily with subcutaneous morphine for 5 days developed reduced analgesia from morphine from days 3 to 5. However, daily administration of kappa agonist U50488H 5 minutes after injection of morphine attenuated the onset of tolerance (Figure 6). Additionally, pre-treatment of kappa receptor antagonist nor-BNI inhibited the tolerance-blocking activity of U50488H. Figure 6. Effect of Kappa Agonist U50488H on Morphine Tolerance. Each point show means  ± standard error. AUC: Area under curve. #: P Although U50488H inhibited the development of tolerance it was unable to inhibit morphine withdrawal (Tao et al., 2008). However, Tao et al. demonstrated that another kappa agonist, LPK-26, may be able to. Chronic doses of morphine, kappa agonist (LPK-26 or U50488H), or both were administered to mice over 5 days and induction of withdrawal was achieved by subcutaneous injection of naloxone 2 hours after the final dose of morphine. Chronic treatment with LPK-26 did not produce a withdrawal response. However, chronic treatment with morphine produced a strong withdrawal response in the form of withdrawal jumping. Furthermore, chronic treatment with morphine along with pre-treatment with LPK-26 had a significant reduction in withdrawal response in a dose dependent manner (Figure 7A). Body weight was also measured before and after naloxone withdrawal induction (Figure 7B). Only LPK-26 showed significant reduction of morphine-induced weight loss. Figure 7. Effects of LPK-26 and U50488H on Withdrawal Jumping and Weight Loss. Data set shown as mean  ± standard error. Reproduced from Tao et al., 2008, p.310. Discussion Analgesic Efficacy of Kappa Opioids Side effects of selective kappa agonists mainly stem from its activity in the central nervous system. These side effects are the main hindrance for pharmacologic use of kappa opioids and include dizziness, dysphoria, confusion, sedation, hallucinations, diuresis, and even psychotic symptoms at high doses (Walsh, Strain, Abreu, Bigelow, 2001). Strategies to minimize these unwanted effects revolve around limiting the activity of kappa agonists to peripheral sites of action. Local injections have been shown to reduce inflammatory pain in animal models through reduced activity of afferent nerve fibres (Auh Ro, 2012; Moon et al., 2016). Although the analgesic results mentioned were limited to animal models, in humans, intravenous administration of peripherally selective formulation CR665 also shows evidence of analgesia for visceral and surgical pain (Arendt-Nielsen et al., 2009; Albert-Vartanian et al., 2016). Furthermore, oral formulations CR665 have been shown to reduce inflammatory osteoarthritic pain in humans (Albert-Vartanian et al., 2016). Continued pain treatment is required if kappa opioids are to be considered as an alternative to mu opioids and research shows viability of kappa opioids in different formulations and routes of administration for the treatment of pain in traditional measures. The components of pain include affective elements as well, which is especially important in chronic pain. Pain affect is comprised of the unpleasant emotions associated with pain as well the emotions towards future implications of having chronic pain. The latter is based on reflections of pain memory and is known as secondary pain affect. As a consequence, chronic pain states can lead to depression and anxiety, which lowers well-being and quality of life (Price, 2000). The amygdala is a crucial structure in the brain involved in emotional learning, pain processing, and constructing of pain memories (Huge et al., 2009). Kappa opioids are able to reduce the activity and inhibit long-term potentiation in the basolateral amygdala. As long-term potentiation is considered a cellular model for learning and memory formation, kappa opioids may be able to prevent or extinguish pain memory and treat affective components of pain. However, this experiment, at the moment, is limited to mice and fu rther study is required to assess whether the results can be translated to human.   Furthermore, these results may be due to structurally specific central actions on the amygdala as other studies show evidence of dysphoric effects from central kappa opioid receptor activation (Lalanne et al., 2014). Although kappa agonists have regularly been shown to provide analgesia in assays using pain-stimulated behaviours as measurements of pain, there is contrast when pain-depressed behaviours are observed instead. Pain-depressed behaviours are behaviours that are decreased due to pain. Some examples that have been tested in animal models are feeding, movement, and reinforced behaviours. In humans, it is analogous to mood or functionality. When pain-depressed behaviours are studied, not only do centrally active kappa agonists fail to relieve pain of this aspect, they may worsen it (Negus et al., 2012; Negus et al., 2015). It should be noted that peripherally active kappa agonists relieve pain in pain-stimulated assays without affecting pain in pain-depressed assays and may be safer than centrally active kappa agonists (Negus et al., 2011). In comparison to kappa opioids, conventional analgesics such as mu opioids and nonsteroidal anti-inflammatory drugs do relieve such components of pain in addition to pain-stimulated behaviours (Negus et al., 2011; Negus et al., 2015). Even so, kappa agonist still have value as they have been shown to reduce pain in human trials as discussed previously. The studies on pain-depressed behaviours have limitations to animal models and further studies are needed to understand how clinically relevant the effects may be for humans. Managing Addiction Some of the major problems of using mu opioids for pain control are the development of tolerance, dependence, and drug abuse, which may all contribute to addiction. Although there are many other drugs that also relieve pain, the difficulty lies in managing addiction at the same time. Kappa agonists, aside from having low abuse potential, have been shown to decrease self-administration of fentanyl in animal models (Negus et al., 2008). These results are promising evidence for kappa agonists being agents to prevent opioid abuse. Also, kappa agonists have additive analgesic effects with mu opioids (Negus et al., 2008; Sakakihara et al., 2016). This possibly reduces the amount of mu opioid required for effective pain management while also reducing addiction and abuse liability due to less use. Increased usage of mu opioids may be due to the development of tolerance, requiring increased dosage to maintain analgesia. The high addictive potential of mu opioids makes this a concerning issue. However, addition of kappa agonists during administration of mu opioids may be able to significantly inhibit the development of tolerance (Hamabe et al., 2008). It may be possible to prevent the development of physical dependence and addiction to mu opioids by adding kappa agonists to drug regimens of chronic pain patients. As for those who are already affected by physical dependence on mu opioids, there is evidence that kappa opioids can inhibit withdrawal symptoms and reduce dependence (Tao et al., 2008). However, some kappa agonists, such as U50488H, do not have any significant effect. It has been suggested that the inconsistency may be due to varying affinities for different subtypes of kappa opioid receptors. Nonetheless, this study demonstrates potential for kappa agonists in managing opioid addiction through modulating dependence and withdrawal. Future studies may provide better understanding on subtype functions and improve designs for desired effects while minimize side effects. Also, as the studies regarding kappa agonist interaction with mu opioids are mainly done on animal models, further investigation is required to see whether results can be extended to humans. One important point to distinguish is non-selective versus peripherally selective kappa agonists. As mentioned previously, activation of kappa receptors in the central nervous system can lead to many side effects. Peripherally selective kappa agonists still produces analgesia, but it is uncertain whether the effects of the kappa agonists on abuse, tolerance, and dependence are due to central or peripheral activity. If these effects are due to central activity, the benefits of kappa agonists for addiction management will be limited by their undesired side effects. Still, in a study involving a peripherally selective kappa agonist and its effects on nicotine, there is some evidence suggesting that activation of peripheral kappa receptors do inhibit symptoms of withdrawal and dependence by inhibiting activity of central kappa receptors. Conclusion In conclusion, this study found that selective kappa agonists provide analgesia to inflammatory, visceral, and surgical pain. In contrast, they were not effective inhibitors of behaviour-depressing effects of pain. Specific activities of kappa receptors in the basolateral amygdala, however, may inhibit affective components of pain.   In managing addiction, kappa agonists may able to prevent mu opioid abuse, prevent the development of tolerance, inhibit the symptoms of withdrawal, and reduce physical dependence. The additive effect with mu opioids and the inhibition of tolerance development can reduce the required amount of mu opioids for effective analgesia, thus reducing abuse and addiction likelihood. Overall, selective kappa agonists are a good prospect for managing pain while combating opioid abuse and addiction. Appendix Evidence Table First Author Date of Publication Study Design Level of Evidence Study Population Therapy or Exposure Outcome/Results Albert-Vartanian 2016 Review 1 Human CR845 CR845 reduced pain with less abuse potential Arendt-Nielsen 2009 Clinical trial 1 Healthy males CR665, Oxycodone CR665 is effective on visceral pain Auh 2012 Animal model 0 Rats U-50488 Local kappa agonist attenuated inflammatory mechanical hyperalgesia Hamabe 2008 Animal model 0 Mice Morphine, U-50488H Analgesic tolerance to morphine is prevented by U-50488H through suppression of PKC Huge 2009 Animal model 0 Mice U-50488H Activation of kappa receptors decrease synaptic transmission and long term potentiation in the amygdala Moon 2016 Animal model 0 Rats U-50488, Nor-BNI U-50488 inhibits nociception in arthritic knee joints of rats Negus 2008 Animal Model 0 Rhesus Monkey Fentanyl, U69593 Addition of kappa agonist to fentanyl demonstrated additive anti-nociception and decreased drug self administration Negus 2011 Animal Model 0 Rats Ffir, ICI204448, Salvinorin A Kappa agonists do not inhibit pain-depressed behaviours Negus 2015 Animal model 0 Mice Morphine, Ketoprofen, U69593 Morphine/Ketoprofen inhibited pain-depressed behaviours whereas U69593 failed to do so Sakakihara 2016 Animal Model 0 Mice Morphine, TRK-820, Nor-BNI Addition of kappa agonist to morphine may have additive anti-nociceptive effects Tao 2008 Animal Model 0 Mice Morphine, LPK-26, U50488H LPK-26 is a potent analgesic with low dependence and inhibits morphine withdrawal

Is Low Self Esteem Linked To Racism?

Is Low Self Esteem Linked To Racism? In the US, racism is a very familiar issue. Racism manifests itself in various ways including police brutality against minorities, racial profiling and affirmative action. Issue like the history of slavery and the rising resentment against immigrants are also quite well known. The truth is, racism is not a thing of the past. Perhaps it has reduced in the past century, but it is still quite alive today. Eradicating racism is one of those processes that cannot happen in an instant, but they happen over a long period of time. Slowly, but surely, we are moving in a positive direction. Low self-esteem has become a frequently repeated explanation for social and personal problems ranging from young peoples involvement in violent crimes to personal failures and racist behaviors. According to psychologists who have researched the topic, racism is about real power, it is not just something that people randomly think about. Social issues like racism are quite complex and multilayered. It partly has to do with issues of economics, political power, and domination. It is also based on how people perceive, interpret, and value differences. Basically, people act in ways that align with their perceptions. People define circumstances in ways that are real to them and also according to the values that they were raised with. It is true that racial groups have things that make them distinct; however people sometimes dwell on negative distinctions as opposed to the positive ones. We humans tend to emphasize stereotypes that relate to our most closely held values. For instance, a group that values intellect may be quick to see another group as inferior in intelligence. Similarly, if loyalty is valued by a group, then it may label others as disloyal. It seems that racism helps racists feel good about themselves and their racial group by focusing on comparisons with other groups. These issues are what give these groups an identity. There are many ways in which people try to feel better about themselves; as individuals and as a group. Seemingly, everyone likes to believe that their racial group is unique but people tend to overestimate the level of positive attributes present in the group. On the other hand, when it comes to negative qualities, people tend to underestimate those. Racism can develop because of limited information. As humans, we find ourselves putting people in categories like good versus bad and friend versus foe. Without these generalized concepts and categories, getting through the day would be highly demanding. Categorization helps us take shortcuts and helps us become more efficient in making decisions. Also, racism towards other groups often leads to feelings of anxiety when we encounter the members of other racial groups. When we are anxious, we tend to avoid what makes us anxious. We simply avoid contact with individuals by hiring someone else for a job, striking up friendships with someon e else we feel more comfortable with, and sitting down at the lunch table with those who seem to be more like us. Racism may help us feel better about ourselves, we avoid challenging our thinking. In other words, we become defensive and protective of our opinions and only reluctantly question our thought patterns. And these ways of thinking helps protect not only our self-esteem, but also privileges and benefits that we have as members of a racial group. For example, racist discrimination which in the past has limited slots available to minority groups at universities has benefitted the majority population by making more slots available to its members. So, maintaining our racist views of others allows us to feel better about our own group and to avoid challenging unfair social practices that benefit us. Furthermore, we as humans seem to put effort into maintaining our views of the world. For example, we may pay attention to information that supports our views. The more strongly we hold a stereotype, the more we tend to remember confirming information about that racial group. For instance, the more we believe that Asian people cannot drive, the more likely we will remember incidents which seem to support these views. We also discount or rationalize information that is contradictory to our belief system. People who do not act according to our stereotype of them stand out to us as different. For example the Black person who is intelligent articulate and the Asian man who is a good driver become exceptions to the rule, but the rule remains. It is almost like when we see someone from a different racial group, we look for those stereotypes that align with our thinking. Racism, Violence Immigrants in the workplace The U.S. legislative system is currently battling over the Immigration bill for workers. Resistance is fierce in the House of Congress to any plan to legalize the estimated 12 million illegal immigrants or to create a program of millions of guest workers who would in turn be put on a path to citizenship. No one accuses House leaders of acting out of racism, but some say they are responding to constituents who are. The House leadership needs to show some progress on the immigration issue to soothe angry anti-immigrant forces in the country. But the President and Senate want guest workers and a path to citizenship as part of any deal. The Democratic allegations of racism may sound like just another political strategy, but there certainly is a case to be made that racial fears are fueling some of the debate on the immigration policy. The political demand to seal the U.S.-Mexico border, and the Presidents new proposal to send 6,000 members of the Army to help, is supposed to be based on national security. But why then is no one proposing sending additional troops to secure the U.S.-Canada border? Most people want to know if the U.S. is trying to stop primarily undocumented Mexican workers rather than terrorists from crossing the border. Figuring out just how many immigrants, Hispanics or otherwise, to let into the country each year is exactly what lawmakers ought to be trying to do as they undertake immigration reform. Setting immigration targets that are in the countrys interest is, after all, the point of having an immigration policy to begin with. Policymakers should be asking questions like: what kinds of skills does America need to import? And how many of them do they need? What advantage is there is in allowing family members to join new citizens, as is currently the policy? Just as important, the debate could address the issue of race head-on: should ethnicity be a factor in granting citizenship? But until politicians define the goals of American immigration policy; who and how many do we want and for what reason, it will be impossible to eliminate the influence of ant i-immigrant forces who, whether racist or not, draw dubious conclusions and make misleading statements. In Canada, immigration reform needs to take place especially to protect long-term care facility workers who are immigrants. Long-term care facility workers include nurses, physical therapists, occupational therapists, administrators etc. Canadian long-term care facilities are violent and dangerous workplaces. This need not be the case, a study found that 43% of personal support workers endure physical violence at work on a daily basis, while another quarter face such violence every week. Most are women, and many are immigrants or from minority racial groups. Violence is a constant and ongoing part of their job. In contrast, they found that levels of violence are much lower in Nordic countries, indicating that the high level of violence in Canadian facilities is exceptional and not a necessary feature of work in long-term care. The study is part of a larger project comparing Canadian long-term care facilities with Nordic European countries. Violence in long-term care is not just a workers issue. It is an immigration issue. The vast majority of care-giving staff are women, many of whom are immigrants and women of color. Personal support workers are the ones who suffer the most. The fact is that much of the violence occurs during direct care activities. Because personal support workers provide the bulk of direct care, they are most frequently exposed to violence. This does not imply that violence does not have an impact on other workers. In fact, the researchers found that 16.8% of registered nurses and 24.6% of licensed practical nurses, and registered nursing assistants experience violence on a daily basis. These numbers are shocking, but they do not come close to the prevalence of daily violence for personal support workers (43%). Workers at 71 unionized long-term care facilities in Manitoba, Ontario and Nova Scotia were surveyed about their experiences of physical violence, unwanted sexual attention and racial comments. They also took part in focus group discussions. The workers were nearly seven times more likely to experience daily violence than workers in Nordic European countries like Denmark, Finland, Norway, and Sweden. Researchers also identified racism and structural violence. This stems from severe working conditions for caregivers who are committed to caring but robbed of the resources to do so. The researchers concluded that long-term caregivers work under conditions that not only foster violence but also render it invisible. Most violent incidents go unreported. Workers are afraid to report violent incidents, fearing that they will be blamed. Or they simply do not have the time to do so because of the paperwork involved. The verbal violence experienced by care workers often includes threats, screaming, cursing, racial insults, and demeaning remarks. The physical violence experienced by care workers typically includes being slapped or hit with an object. It frequently involves being pinched, bitten, having ones hair pulled, being poked or spit on. Having ones wrists painfully twisted is also common. Unwanted sexual attention was also frequently experienced by those surveyed. Approximately one third said they experienced unwanted sexual attention on a daily or weekly basis. Over 11% of the staff said they encountered racist comments on a daily or weekly basis. According to the research, this is likely an underestimation of workplace racism. A large number of workers from minority groups work in large urban centers with high likelihood of racism. Also, the questionnaires were available only in English and workers were required to fill them out alone, so workers with language barriers are underrepresented. In focus group discussions, many workers reported that they personally experienced or overheard racism at work. Long-term care workers link violence and racism with working conditions. Having too much to do, working with too little time and too few resources places workers in dangerous situations. Working short-staffed is a major contributor. Canadian personal support workers reported that they routinely work short-staffed. Almost half say they do so every day. And over one third felt that they are too often left alone to care for residents. When these working conditions were compared to those of the citizens of Nordic countries, they just could not match up. Immigrants and minorities are simply not treated the same as non-immigrants and non-minorities. What can one person do? I recently read the story of a lady who currently resides in Canada but was born in the Philippines. A few years ago, the woman had a very difficult decision to make. She gave birth to her son in Canada and had the impossible choice between an impoverished life for him in the Philippines, or leaving him with strangers in Canada. Now Salvador, a Filipino migrant domestic worker in Montreal, is campaigning against what she calls the systemic racism and sexism of the Canadian governments Live-in Caregiver program. Salvador entered Canada in 1995 as one of thousands of Filipino workers in the Live-in Caregiver Program (LCP). The LCP is an initiative of Citizenship and Immigration Canada, allowing foreign workers (almost always women) to enter Canada as domestic workers living in their employers home. Salvador earns $271 for a 49-hour week and after taxes takes home $221. After completing 24 months of work within 3 years of arriving, caregivers are allowed to apply for landed immigrant status. For Salvador, the choice to come to Canada was a matter of life and death for her family. She felt that she had no choice but to move to Canada. Even with the LCP, applicants pay fees to their own government, to the Canadian and Quebec governments, to the employment agency, and for their travel. For Salvador this amounted to over $4700 Canadian. This was such a large sum of money for Salvador and she struggled to gather the money. Colonialism and global capitalism have created a situation in the Philippines where its economy is dependent on transnational corporations, where low-wage contract work, poverty and unemployment are rampant, and where 2000 workers leave the country daily in search of a livelihood. It seems like the Canadian governments need for cheap labor and the Labor Export Policy of the Philippines makes the LCP a functional system. The government of the Philippines systematically pushes Filipinos out of the country, so that they can earn money abroad. Meanwhile, there are millions of dollars being sent back to the Philippines by these migrants. Salvador has been elected vice-chairperson of Pinay, a Filipino womens advocacy and support organization. Pinay gives caregivers information, advice, and guidance through the problems they may encounter with employers, agencies, and the government. Many of its members are current and former caregivers who call strongly for the LCP to be overhauled or abolished. The Canadian Filipino community in general also wants the program scrapped and campaigns across Canada on the issue. Critics of the LCP say that significant problems arise for migrant workers under the program. As caregivers live in the home, they often work unpaid overtime, including extra tasks such as cleaning, cooking and tutoring. Theoretically, live-in caregivers are granted basic rights such as access to employment insurance, pregnancy leave, overtime pay, vacations and paid holidays. The law states that people with complaints about their employers should file them with the appropriate Commissioner in Quebec. And if the caregiver is fired, they are still allowed to find another employer in the meantime. But there is a gap between the theory and the reality that caregivers face. One problem Salvador finds with this procedure is that if a caregiver is fired, whether or not she files a complaint, the 4-6 month waiting period for a new work permit is too long. In Salvadors case, when her employers learned she was pregnant, they fired her. She was not allowed to work between permits, eventually could not fulfill the 24-month requirement. She says some employers considered her to be unwanted. In contrast, a pregnant colleague heeded her employers suggestion to have an abortion, kept her job, and eventually became an immigrant. Salvador was unable to fulfill the immigration requirements because she was pregnant, gave birth and was fired. If she was a man, of course she would have no problem fulfilling the 24 months. Salvador did not comply with her first order to leave the country, as she has filed an appeal to remain in Canada on humanitarian grounds. She met with an immigration official, however, and was told to leave the country or be deported by force. According to Salvadors affidavit, the immigration officer found that the applicants volunteer work with three local community organizations did not show integration into Canadian society, because the organizations exist to help persons of Filipino origin. When a local member of the National Action Committee of the Status of Women found out about the situation, she was outraged. She could not believe that helping the Filipino Canadian community was not considered tangible. This is pure discrimination and racism. Furthermore, although an employer made known his willingness to hire her, the immigration officer expressed doubts that Salvador could find a job in Canada. But throughout her irregular employment, she had never let herself become a burden to the Canadian government. Neither was she ever a burden to the government of her country. Some of the caregivers were skilled workers such as nurses or accountants in the Philippines, but in Canada are confined to domestic care giving, jobs that Canadians do not want to do. Salvador was always willing to be a care giver, as long as she is able to obtain residency status. All she wants is a better life for her family. For example, when Canada brought in foreign nurses to fill demand, they were given status. In fact, the work of care givers allows both Canadian parents to work and contribute to Canadian society. Care givers also contribute taxes and fees to the Canadian government, which is if great benefit to them. Salvador points out that the Canadian government saves money importing the cheaper labor of women from developing countries, instead of instituting a national childcare program. Basically, the government is filling a public need with a private solution. Her affidavit states that the immigration officer suggested that her son should be left behind in Canada. It is believed that he would not suffer trauma due to separation from only one parent, as he has never seen his father. How outrageous this is. Salvadors lawyer argues that Salvador and her son should remain in Canada for humanitarian reasons. Her son is a Canadian citizen, and as a result he has all the rights accorded to a Canadian citizen, including the Constitutional right to live in Canada. If the mother is deported, his rights would be violated, either the right to live in Canada if deported along with his mother, or the right to security of the person if he stays in Canada because he would be separated from his mother, the only parent he has ever know. Salvador was refused an extension on her work permit. She should theoretically be granted all the rights and access to services of any other Canadian citizen, including access to health care. Salvador was not able, however, to renew her sons Medicare card when her employment authorization ran out. The Campaign to Stop the Exploitation of Melca Salvador has included many community members and students in research, letter-writing campaigns, media outreach, raising legal funds, organizing demonstrations, and distributing information. Petitions and letters of support have been received from migrant worker communities around the world. Their press release states that LCP critics insist deporting women live-in caregivers such as Salvador and others in several recent cases, is unjust on humanitarian grounds. These women are not disposable commodities that Canada can use and dump at will. Demands for the Canadian government include allowing Salvador to remain in Canada with her son Richard, recognizing the rights and contributions of foreign caregivers and nannies to Canada, granting Melca and all LCP workers residency now, and abolishing the LCP as it now exists. In many cases these women are overworked and underpaid but because they have to complete 24 months of work within 3 years just to apply for residency status, they put up with it. Campaign members are organizing a Canada-wide day of protest in support of Salvador, which is Thursday, October 19th. They hope to reverse her deportation order so that she can stay with her son. Unfortunately, the federal government does not seem ready to hear their critiques of the LCP. It does not seem like there are any changes planned for the LCP, not even a re-evaluation of the programs impact. Recently, several Canadian Filipino activists insisted on meeting Canadas Minister of Citizenship and Immigration, to discuss their co ncerns. Conclusion By changing our behavior, for example, putting ourselves in close situations with members of other racial groups, we increase our familiarity with these individuals. As we become more familiar with them, we naturally see that we are more alike than different. Not all contact will lead to positive attitude changes. It seems the contact is best if structured; encounters among equals who are cooperating to achieve a common goal. These kinds of behavioral activities are some of the most effective ways to change prejudice against people of other races.

Lockie Leonard And Lex And Rory :: essays research papers

Lockie Leonard and Lex and Rory English Lockie Leonard and the film Lex and Rory promote the same issues as each other, especially concerning male/female relationships. The issues are showed differently. The woman is the one who is pressured into having a sexual relationship. In this case it is the male who is pressured into having a sexual relationship. As this happens different views, feelings and emotions are shown by the way they deal with the choices they make.   Ã‚  Ã‚  Ã‚  Ã‚  Both Lex and Rory are presented as particular characters. Lockie is shown as a free teenager, he is not tied down and is able to do what he wants. He is just learning about sex and you need to know. â€Å"It’s time we thought about sex† said his mum. This already shows that Lockie is not ready for a sexually involved relationship. He is the typical stereotyped school boy who is in constant trouble with school teachers. â€Å"Outside, get out of my room before I tear your head off and use for a blackboard duster.† Yelled his teacher. Lex on the other hand is a boy lacking self confidence and has a negative outlook on life. He is classed as a nerd because he studies and takes notice of his future planning. Girls are his problem. He is scared of communication and contact. This is one of his main fears, especially talking. In particular talking to one girl called Dai. Due to this not many people pay attention to him except his one and only true fr iend Rory. Lex is the type of person who is afraid to make the first move, but having a friend like Rory it starts to become easier.   Ã‚  Ã‚  Ã‚  Ã‚  Lockie doesn’t change himself to make other people feel happy. He likes who he is and believes in himself. Lockie doesn’t change for people. He feels that people have to like him for who he is and not for who they want him to be. Lockie doesn’t let his popularity come over him. He will not satisfy anyone, if that is not what he wants to do. Lockie is his own person he is the only person who takes control of his body and mind. Lex has problems with coping with who he is. He feels that girls won’t like him because he is noticed as a nerd. He tries to change who he is to become a better presented person.

Computer-Based Training :: Business Essays

Computer-Based Training Computer-based training can be found in almost all segments of business and education today. "Virtually every major corporation has turned to computer-based training for teaching employees everything from company regulations, to compliance, to factory operations (Rothfeder 1998) Candice Harp (1998) adds that "Corporate spending for training has risen to over $40 billion each year and a recent survey of Fortune 500 companies found that in some industries, companies dedicate as much as 5 percent of their information system budgets to training" (Harp, Taylor et al. 1998) For one thing, the economics make sense. "Employees can be trained at their desktops no matter where they're based, without incurring travel, hotel and meal costs, and there’s no lost productivity from the time spent traveling" (Rothfeder 1998) But exactly what is computer-based training and what are the various forms it takes? Background In general, computer-based training consists primarily of occupational training for adults, as opposed to computer-aided instruction used mainly in educational settings with younger populations. Training refers to any means of delivering information to people so they can do their jobs better. Computer-based training is delivered using computer tutorials in place of live instructors in a classroom format or video taped instruction. Computer-based training is usually interactive, self-paced, learner-directed, and offers immediate feedback to learners. The various forms of computer-based training currently available include interactive CD-ROM tutorials, multimedia simulations, and most recently, internet and intranet-based programs. Some of the numerous examples where computer-based training has been successfully implemented include instruction for bankers regarding corporate policies, Marine Corps fire teams, airline baggage handlers, MBA’s learning economics, and hostage rescue situations. One of the more sophisticated programs even simulates business war games where profits and losses vary based on management-trainee decisions. Advantages "Adult learning theory postulates that adult learners prefer a high degree of learner control. Computer-based training provides more learner control than other forms of training because it allows the learner to select the appropriate time to engage in learning and which topics will be covered" (Harp, Taylor et al. 1998) Another factor in adult learning theory suggests that adults are motivated by relevance of information to their current needs. With computer-based training, "on-demand training is possible for such instances as mechanics using animated, multimedia reference manuals to learn how to correctly install a new part in a car (Bowman, Grupe et al. 1995) Since most of computer-based training is aimed at adult populations, this advantage is a key factor to its popularity.